Clinical Efficacy Evaluation of Sirolimus in Congenital Hyperinsulinism.
Somayyeh HashemianReza Jafarzadeh EsfehaniSiroos KarimdadiRahim VakiliDaniel ZamanfarAmir Hossein SahebkarPublished in: International journal of endocrinology (2020)
This study suggested that sirolimus therapy needs further evaluation to determine which patients will benefit the most. The genetic basis of CHI may have possible implications for determining the patient's response.