Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy.
Yong QinKathryn BollinMariana Petaccia de MacedoFernando CarapetoKevin B KimJason RoszikKhalida M WaniAlexandre ReubenSujan T ReddyMichelle D WilliamsMichael T TetzlaffWei-Lien WangDan S GombosBita EsmaeliAlexander J LazarPatrick HwuSapna Pradyuman PatelPublished in: Journal for immunotherapy of cancer (2021)
Our study provides critical insight into immune profiles of UM primary and metastatic tumors, which suggests a baseline tumor immune signature predictive of response and resistance to immunotherapy in UM.