The Role of Bariatric Surgery in Abdominal Organ Transplantation-the Next Big Challenge?
Tomasz DziodzioMatthias BieblRobert ÖllingerJohann PratschkeChristian DeneckePublished in: Obesity surgery (2018)
Obesity is linked to inferior transplant outcome. Bariatric surgery (BS) is an established treatment of morbid obesity. We provide an overview on BS in the field of kidney (KT) and liver transplantation (LT). In end-stage renal disease (ESRD) and KT patients, BS seems safe and feasible. Complication rates were slightly higher compared to the non-transplant population, whereas weight loss and improvement of comorbidities were comparable. Sleeve gastrectomy (SG) was the preferred procedure before KT and superior to gastric bypass (GB) in regard to mortality and morbidity. If conducted after KT, both procedures showed comparable results. BS before LT was associated with high complication rates, in particular after GB. Albeit distinct complications, SG conducted after LT showed the best results. Immunosuppression (IS) changes after BS were rare.
Keyphrases
- weight loss
- bariatric surgery
- end stage renal disease
- gastric bypass
- chronic kidney disease
- peritoneal dialysis
- roux en y gastric bypass
- obese patients
- weight gain
- risk factors
- glycemic control
- metabolic syndrome
- machine learning
- ejection fraction
- big data
- stem cells
- mesenchymal stem cells
- skeletal muscle
- coronary artery disease
- physical activity
- adipose tissue
- body mass index
- high fat diet induced