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Leptin Levels of the Perinatal Period Shape Offspring's Weight Trajectories through the First Year of Age.

Francesca GarofoliIolanda MazzucchelliMicol AngeliniCatherine KlersyVirginia Valeria FerrettiBarbara GardellaGiulia Vittoria CarlettiArsenio SpinilloChryssoula TziallaStefano Ghirardello
Published in: Nutrients (2022)
Leptin might play a role in neonatal growth trajectories, characterized by an inverse correlation with maternal plasma and milk. PT infants showed the highest correlation with hormone levels, regardless of source, seeming the most affected group by leptin guidance. Low leptin levels appeared to contribute to critical neonates' ability to recover a correct body weight at 1 year. An eventual non-physiological "catch-up growth" should be monitored, and leptin perinatal levels may be an indicative tool. Further investigations are needed to strengthen the results.
Keyphrases
  • body weight
  • depressive symptoms
  • pregnant women
  • body mass index
  • physical activity
  • high fat diet
  • preterm infants
  • weight gain
  • adipose tissue