Promoting Glutathione Synthesis: A Possibility for Treating Cardiomyopathy Induced by a Maternal Western Diet.

Jialing ZhangJiayu WangDa XuYiting GuiFan BaiYu HuoLi Cao Yonghao Gui

Published in: Nutrients (2024)

N-acetylcysteine mitigated cardiomyopathy induced by a maternal Western diet by bolstering glutathione synthesis and enhancing GPx activity, thereby scavenging mitochondrial ROS and modulating oxidative phosphorylation pathways.

Keyphrases

birth weight
physical activity
weight loss
heart failure
south africa
pregnancy outcomes
oxidative stress
cell death
signaling pathway
reactive oxygen species
gestational age
weight gain
protein kinase
body mass index
atrial fibrillation