Effect of Laser-Assisted Reconstructive Surgical Therapy of Peri-implantitis on Protein Biomarkers and Bacterial Load.
Riccardo Di GianfilippoChin-Wei WangYuying XieJanet KinneyJames SugaiWilliam V GiannobileHom-Lay WangPublished in: Clinical oral implants research (2023)
Reconstructive therapy of peri-implantitis significantly altered PICF protein biomarker and microbial levels during the healing process. The adjunctive use of Er:YAG laser significantly modulated the inflammatory response through reduced levels of MMP-9 and VEGF during the post-surgical period. The bacterial load was reduced immediately after therapy, but recolonization was observed by 4 weeks in both groups.