Glucocorticoid effects on bone strength in children with renal diseases.

Jun AoyagiTakahiro KanaiTakane ItoJun OdakaTakashi SaitoHiroyuki BetsuiMasanori KurosakiTomomi MaruTakanori Yamagata

Published in: Nephrology (Carlton, Vic.) (2020)

This study clarified the following three points regarding GC effects on bone strength in children with ISSNS or IgAN: first, S-ALP is a more sensitive bone quality marker than S-TRACP-5b; second, BMD loss was observed only when both S-ALP and S-TRACP-5b levels decreased, and third, S-ucOC levels do not directly reflect bone strength.

Keyphrases

bone mineral density
soft tissue
bone loss
young adults
bone regeneration
body composition
quality improvement