TINU: A Multisystemic Inflammatory Disorder-Case Report and Literature Review.
Juan Montejo-HernándezJorge Rico-FontalvoJosé CabralesShuchi AnandMaría Cristina Martínez-ÁvilaClaudia Duran-MerinoLuis Arias-RestrepoCamilo Andrés Gómez DuranPublished in: Case reports in nephrology (2024)
Background . The syndrome of tubulointerstitial nephritis and uveitis (TINU) is a rare oculorenal condition, mainly seen in children and women. The underlying cause of this disease is unknown. Case Presentation . We report a 24-year-old male without any past medical history, diagnosed with bilateral uveitis and azotemia. Biopsy revealed tubulointerstitial nephritis, consistent with TINU syndrome. Fluorescein angiogram revealed peripheral retinal vasculitis. Discussion . TINU is a rare disorder that needs to be distinguished from sarcoidosis, Sjogren's disease, and tuberculosis. Treatment is indicated in patients with progressive renal insufficiency, consisting of steroid therapy. Most patients recover kidney function. Its early recognition is important to offer the best chance of organ preservation.
Keyphrases
- case report
- end stage renal disease
- juvenile idiopathic arthritis
- ejection fraction
- ankylosing spondylitis
- chronic kidney disease
- newly diagnosed
- young adults
- healthcare
- multiple sclerosis
- single cell
- peritoneal dialysis
- mycobacterium tuberculosis
- prognostic factors
- oxidative stress
- emergency department
- polycystic ovary syndrome
- ultrasound guided
- adipose tissue
- metabolic syndrome
- pulmonary tuberculosis
- stem cells
- pregnant women
- hiv aids
- hiv infected
- fine needle aspiration
- skeletal muscle
- pregnancy outcomes
- adverse drug
- disease activity