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Changes in FeNO, d-ROMs, and BH 4 by Intravenous L-Arginine in Children and Its Putative Role in Asthma Treatment.

Naho YamamotoSaki KasugaDaijiro KabataMyu OnoSakura AndoTaisuke HashimotoShiori FujikawaHiroko FujitaniAyumi ShintaniTakashi Hamazaki
Published in: Journal of asthma and allergy (2024)
The administration of L-arginine increased the NO level and decreased the d-ROMs level. Due to this, biopterin may be consumed and decreased, leading to an increase in the d-ROMs level. As a reduction in reactive oxygen species leads to the relief of inflammation, arginine and biopterin may be useful for inhibiting inflammation.
Keyphrases
  • nitric oxide
  • reactive oxygen species
  • oxidative stress
  • young adults
  • signaling pathway
  • amino acid
  • lung function
  • high dose
  • low dose