Nonmalignant portal vein thrombi in patients with cirrhosis consist of intimal fibrosis with or without a fibrin-rich thrombus.
Ellen G DrieverFien A von MeijenfeldtJelle AdelmeijerRobbert J de HaasMarius C van den HeuvelChandrasekaran NagasamiJohn W WeiselConstantino FondevilaRobert J PorteAnabel BlasiNigel HeatonStephen GregoryPauline KaneWilliam BernalYoh ZenJ P LuyendykPublished in: Hepatology (Baltimore, Md.) (2021)
We demonstrate that PVT in patients with cirrhosis consists of intimal fibrosis with an additional fibrin-rich thrombus in only one-third of cases. We hypothesize that our observations may explain why not all portal vein thrombi in patients with cirrhosis recanalize by anticoagulant therapy.