Whole-body distribution of tenofovir, emtricitabine and dolutegravir in non-human primates.

Thibaut GeléHélène GougetNastasia DimantValérie FurlanJon CollinsErin M B ScholzChris M ParryRoger Le GrandOlivier LambotteDelphine DesjardinsAurélie Barrail-Tran

Published in: The Journal of antimicrobial chemotherapy (2024)

Overall, this study determines the first whole-body distribution in a validated NHP model. These data have important implications for future preclinical and clinical studies for the development of novel HIV therapies towards an HIV cure.

Keyphrases

antiretroviral therapy
hiv infected
hiv positive
human immunodeficiency virus
hiv infected patients
hiv aids
hiv testing
hepatitis c virus
endothelial cells
men who have sex with men
electronic health record
big data
south africa
stem cells
machine learning
cell therapy
bone marrow