Difference in Rupture Risk Between Familial and Sporadic Intracranial Aneurysms: An Individual Patient Data Meta-analysis.

Charlotte C M ZuurbierLiselore A MensingMarieke J H WermerSeppo Juvela Antti E LindgrenTimo KoivistoJuha E JääskeläinenTomosato YamazakiRob Molenberg J Marc C van Dijk Maarten UyttenboogaartMarlien AalbersAkio MoritaShinjiro TominariHajime AraiKazuhiko NozakiYuichi MurayamaToshihiro IshibashiHiroyuki TakaoGabriel J E RinkelJacoba P GrevingYnte M Ruigrok

Published in: Neurology (2021)

The risk of rupture of UIA is 2.5 times higher, with a range from a 1.2 to 5 times higher risk, in familial than in sporadic UIA. When assessing the risk of rupture in UIA, family history should be taken into account.

Keyphrases

systematic review
late onset
early onset
amyotrophic lateral sclerosis
case report
electronic health record
big data
machine learning
deep learning