LOXL1-AS1 contributes to metastasis in sonic-hedgehog medulloblastoma by promoting cancer stem-like phenotypes.

Anh Duy DoKuo-Sheng WuShing-Shung ChuLe Hien GiangYu-Ling LinChe-Chang ChangTai-Tong WongChia-Ling HsiehShian-Ying Sung

Published in: Journal of experimental & clinical cancer research : CR (2024)

This study proved the functional significance of LOXL1-AS1 in SHH-MB metastasis by its promotion of TGF-β2-mediated cancer stem-like phenotypes, providing both prognostic and therapeutic potentials for targeting SHH-MB metastasis.

Keyphrases

papillary thyroid
squamous cell
squamous cell carcinoma
childhood cancer
drug delivery