Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome.
Abram B KamizaLing-Ling HsiehReiping TangHuei-Tzu ChienChih-Hsiung LaiLi-Ling ChiuTsai-Ping LoKuan-Yi HungJeng-Fu YouWen-Chang WangChao A HsiungChih-Ching YehPublished in: Molecular genetics & genomic medicine (2018)
Our findings revealed that polymorphisms of DNA repair genes that include NUDT1, ERCC2, and MUTYH are associated with CRC in patients with Lynch syndrome in Chinese population. Further studies with large sample size are needed to confirm our findings.