Molecular mutations as a possible factor for determining extent of thyroid surgery.
Joshua R KrasnerNourah AlyouhaMarc PusztaszeriVeronique-Isabelle ForestMichael P HierGalit AviorRichard J PaynePublished in: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (2019)
In this study, BRAF V600E, RET/PTC1 rearrangement, and TERT mutations were associated with aggressive behaving thyroid malignancies as defined above. Molecular testing may be a useful method to anticipate aggressive tumour types and therefore assist in planning the extent and timing of surgery.