Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice.

Jacqueline M StephensJennifer L BaileyHardy HangVictoria RittellMarilyn A DietrichRandall L MynattCarrie M Elks

Published in: Obesity (Silver Spring, Md.) (2019)

The chow-fed OSMRFKO mice exhibited adipose tissue dysfunction and increased proinflammatory adipokine production. These results suggest that intact adipocyte oncostatin M-OSMR signaling is necessary for adipose tissue immune cell homeostasis.

Keyphrases

adipose tissue
insulin resistance
high fat diet induced
high fat diet
oxidative stress
metabolic syndrome
type diabetes
skeletal muscle
body mass index