Deferiprone attenuates neuropathology and improves outcome following traumatic brain injury.
Maria DaglasPhan H TruongLinh Q MilesSydney M A JuanShalini S RaoPaul A AdlardPublished in: British journal of pharmacology (2022)
Our findings support a detrimental role of iron in the injured brain and suggest that deferiprone (or similar iron chelators) may be promising therapeutic approaches to improve survival, functional outcomes and quality of life following TBI.