On the road to replacing invasive testing with cell-based NIPT: Five clinical cases with aneuploidies, microduplication, unbalanced structural rearrangement, or mosaicism.

Else Marie VestergaardRipudaman SinghPalle ScheldeLotte HattKatarina RavnRikke ChristensenDorte Launholt LildballeOlav Bjørn PetersenNiels UldbjergIda Vogel

Published in: Prenatal diagnosis (2017)

Aneuploidy and subchromosomal aberrations can be detected using fetal cells harvested from maternal blood. The method has the future potential of being offered as a cell-based NIPT with large high genomic resolution.

Keyphrases

single cell
cell therapy
induced apoptosis
copy number
gene expression
physical activity
birth weight
current status
cell proliferation
cell death
weight gain
gestational age