In vitro synergistic effect of hesperidin and doxorubicin downregulates epithelial-mesenchymal transition in highly metastatic breast cancer cells.

Nur Dina AmalinaIrfani Aura SalsabilaUmmi Maryam ZulfinRiris Istighfari JenieEdy Meiyanto

Published in: Journal of the Egyptian National Cancer Institute (2023)

These findings strongly suggest that Hsd possesses a potential synergistic effect that can be developed to enhance the anticancer efficacy of DOX and reduce the risks of chemotherapy use in highly metastatic breast cancer.

Keyphrases

metastatic breast cancer
epithelial mesenchymal transition
breast cancer cells
human health
squamous cell carcinoma
small cell lung cancer
transforming growth factor
drug delivery
locally advanced
signaling pathway
cancer therapy
rectal cancer