Rapid-Acting Antidepressants: Mechanistic Insights and Future Directions.
Danielle M GerhardRonald S DumanPublished in: Current behavioral neuroscience reports (2018)
The discovery that ketamine produces rapid therapeutic actions for depression and suicidal ideation represents a major breakthrough and much needed alternative to currently available medications. However, novel fast acting agents with fewer side effects are needed, as well as elucidation of the efficacy of these rapid-acting antidepressants for depression in women.
Keyphrases
- loop mediated isothermal amplification
- depressive symptoms
- major depressive disorder
- sleep quality
- high throughput
- pregnancy outcomes
- current status
- pain management
- metabolic syndrome
- physical activity
- pregnant women
- adipose tissue
- insulin resistance
- chronic pain
- skeletal muscle
- bipolar disorder
- sensitive detection
- breast cancer risk