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Variants at the OCA2/HERC2 locus affect time to first cutaneous squamous cell carcinoma in solid organ transplant recipients collected using two different study designs.

L WeiD C AllainM N BernhardtJ L GillespieS B PetersO H IwenofuH H NelsonS T ArronAmanda Ewart Toland
Published in: The British journal of dermatology (2017)
This study is the first to show an association between OCA2/HERC2 variants and time to first cSCC post-transplant. This may impact dermatological screening recommendations for high-risk populations.
Keyphrases
  • squamous cell carcinoma
  • copy number
  • radiation therapy
  • dna methylation
  • genome wide
  • genetic diversity