A Dynamic Data Correction Method for Enhancing Resolving Power of Integrated Spectra in Spectroscopic Analysis.
Chih-Hao HsiaoYin-Hung LaiShu-Yun KuoYi-Hong CaiCheng-Huang LinYi-Sheng WangPublished in: Analytical chemistry (2020)
A dynamic data correction method embedded in the process of data acquisition improves spectral quality. The method minimizes the impact of random errors in spectroscopic measurements by correcting peak positions in every single-scan spectrum. The method is fast enough to facilitate online data correction. The integration of corrected spectra improves resolving power and signal-to-noise ratio. The correction method can apply to most analytical spectra. In mass spectrometry and Raman spectroscopy, observations show that it improved the average resolving power by roughly 40-150% and revealed unresolved spectral features.
Keyphrases
- electronic health record
- mass spectrometry
- big data
- raman spectroscopy
- computed tomography
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- liquid chromatography
- optical coherence tomography
- high resolution
- healthcare
- magnetic resonance imaging
- air pollution
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- patient safety
- deep learning
- dual energy
- ms ms
- simultaneous determination
- capillary electrophoresis