CXCL1 is upregulated during the development of ileus resulting in decreased intestinal contractile activity.
Tibor DocsaDeepa BhattaraiAdam SiposCharles E WadeCharles S CoxKaren UrayPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)
These data suggest that CXCL1, released from macrophages during intestinal wall stress, can suppress intestinal contractile activity. CXCL1 is a potential target for preventing or treating ileus in trauma patients.