CXCL1 is upregulated during the development of ileus resulting in decreased intestinal contractile activity.

Tibor DocsaDeepa BhattaraiAdam SiposCharles E WadeCharles S CoxKaren Uray

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2019)

These data suggest that CXCL1, released from macrophages during intestinal wall stress, can suppress intestinal contractile activity. CXCL1 is a potential target for preventing or treating ileus in trauma patients.

Keyphrases

trauma patients
skeletal muscle
smooth muscle
risk assessment
artificial intelligence
deep learning
small bowel