Responses of hematopoietic cells after ionizing-irradiation in anemic adult medaka ( Oryzias latipes ).

Kento NagataKeita OhashiChika HashimotoAlaa El-Din Hamid SayedTakako YasudaBibek DuttaTakayuki KajiharaHiroshi MitaniMichiyo SuzukiTomoo Funayama Shoji Oda Tomomi Watanabe-Asaka

Published in: International journal of radiation biology (2022)

The results obtained strongly suggest that the hematopoietic stem cells in medaka kidney prioritize to proliferate and increase peripheral blood cells to eliminate anemia, even when they are damaged by high-dose irradiation.

Keyphrases

induced apoptosis
stem cells
high dose
peripheral blood
cell cycle arrest
low dose
bone marrow
radiation induced
chronic kidney disease
radiation therapy
young adults
cell therapy
iron deficiency