Aging-Associated ALKBH5-m 6 A Modification Exacerbates Doxorubicin-Induced Cardiomyocyte Apoptosis Via AT-Rich Interaction Domain 2.
Runtai ChenGuo-Gang ZhangKun SunAlex F ChenPublished in: Journal of the American Heart Association (2023)
A modification in modulating doxorubicin-induced cardiac dysfunction, remodeling, and cardiomyocyte apoptosis in male mice. These results highlight the potential of ALKBH5-targeted treatments for elderly patients with cancer in clinical settings.