Crystal structure and Hirshfeld surface analysis of (2 2 RS ,2 3 SR ,2 5 RS ,2 6 SR )-2 3 ,2 5 ,5-trimethyl-2 1 -(2,2,2-tri-fluoro-acet-yl)-5-aza-2(2,6)-piperidina-1,3(2,5)-di-furana-cyclo-hexa-phan-2 4 -one.

The title compound, C 20 H 21 F 3 N 2 O 4 , features a main twelve-membered difuryl ring with which the furan rings make dihedral angles of 76.14 (5) and 33.81 (5)°. The dihedral angle between the furan rings is 42.55 (7)°. The six-membered nitro-gen heterocycle has a twist-boat conformation. In the crystal, pairs of mol-ecules are connected by inter-molecular C-H⋯O inter-actions, generating an R 2 2 (14) ring motif. These pairs of mol-ecules form zigzag chains along the a -axis direction by means of C-H⋯F inter-actions. Furthermore, C-H⋯π and C-F⋯π inter-actions link the mol-ecules into chains along the b- axis direction, forming sheets parallel to the (001) plane. These sheets are also connected by van der Waals inter-actions.