The histone modification reader ZCWPW1 promotes double-strand break repair by regulating cross-talk of histone modifications and chromatin accessibility at meiotic hotspots.

Shenli YuanTao HuangZiyou BaoShiyu WangXinyue WuJiang LiuHongbin LiuZi-Jiang Chen

Published in: Genome biology (2022)

Taken together, our findings provide new insights into how histone modifications and their associated regulatory proteins collectively regulate meiotic homologous recombination.

Keyphrases

dna methylation
dna damage
dna repair
transcription factor
gene expression
genome wide