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mSphere of Influence: an Army Marching on Its Stomach-Malaria Parasites Sense and Subvert Host Nutrition.

Clare R Harding
Published in: mSphere (2021)
Clare Harding works on the metal biology of the parasite Toxoplasma gondii In this mSphere of Influence article, she reflects on how two papers from the laboratory of Maria Mota, "Host-mediated regulation of superinfection in malaria" by Portugal et al. (S. Portugal, C. Carret, M. Recker, A. E. Armitage, et al., Nat Med 17:732-737, 2011, https://doi.org/10.1038/nm.2368) and "Nutrient sensing modulates malaria parasite virulence" by Mancio-Silva et al. (L. Mancio-Silva, K. Slavic, M. T. Grilo Ruivo, A. R. Grosso, et al., Nature 547:213-216, 2017, https://doi.org/10.1038/nature23009), made an impact on her understanding of host-pathogen interactions by examining the complex interplay between parasites and their hosts' nutritional status.
Keyphrases
  • plasmodium falciparum
  • toxoplasma gondii
  • escherichia coli
  • pseudomonas aeruginosa
  • staphylococcus aureus
  • photodynamic therapy
  • biofilm formation
  • candida albicans
  • antimicrobial resistance