Association of Serum Neurofilament Light Chain With Inner Retinal Layer Thinning in Multiple Sclerosis.
Elias S SotirchosEleni S VasileiouAngeliki G FilippatouKathryn C FitzgeraldMatthew D SmithHannah-Noelle LordGrigorios KalaitzidisJeffrey LambeAnna DuvalJerry L PrinceEllen M MowryShiv SaidhaPeter A CalabresiPublished in: Neurology (2022)
Elevated baseline sNfL is associated with accelerated rates of retinal neuroaxonal loss in relapsing-remitting MS, independent of overt ON, but may be less reflective of retinal neurodegeneration in progressive MS.