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May We Use Non-Invasive Indices of Aortic Stiffness and Endothelial Glycocalyx as Biomarkers for Idiopathic Pulmonary Artery Hypertension Follow-Up?

Helen TriantafyllidiDionysia BirmpaDimitrios BenasIgnatios IkonomidisAntonis SchoinasParaskevi TrivilouFrantzeska FrantzeskakiStylianos E Orfanos
Published in: Medicina (Kaunas, Lithuania) (2021)
Idiopathic pulmonary arterial hypertension (IPAH) initial evaluation and follow-up, a rare and incurable disease if left untreated, is based on a multiparametric approach (functional status of the patient, biomarkers, hemodynamic parameters and imaging evaluation of right heart impairment). Arterial stiffness (AS) and endothelial glycocalyx are indices of systemic circulation. We present the 3-years follow-up of a female IPAH patient. We propose aortic stiffness and endothelial glycocalyx indices as non-invasive markers of either improvement or deterioration of IPAH disease.
Keyphrases
  • pulmonary artery
  • pulmonary arterial hypertension
  • pulmonary hypertension
  • coronary artery
  • endothelial cells
  • blood pressure
  • case report
  • heart failure
  • left ventricular
  • fluorescence imaging
  • aortic dissection