Associations of plasma neurofilament light chain and progranulin with frailty in older adults.

Wan-Hsuan LuKelly Virecoulon GiudiciSophie GuyonnetGeetika AggarwalAndrew D NguyenJohn E MorleyBruno VellasPhilipe de Souto Barretonull null

Published in: Journal of the American Geriatrics Society (2021)

This study failed to find associations of circulating NfL and PGRN levels with frailty among community-dwelling older adults in adjusted analyses. Whether plasma neurodegenerative markers serve as potential biomarkers of frailty requires further investigation.

Keyphrases

community dwelling
physical activity