Interaction of Alcohol Consumption and ABCG2 rs2231142 Variant Contributes to Hyperuricemia in a Taiwanese Population.

I-Chieh ChenYen-Ju ChenYi Ming ChenHsueh-Ju LinYing-Cheng LinJui-Chun ChagnPei-Chun ChenChing-Heng Lin

Published in: Journal of personalized medicine (2021)

the ABCG2 rs2231142 is a crucial genetic locus for sUA levels in the Taiwanese population and our findings revealed that alcohol consumption combined with the ABCG2 rs2231142 risk allele contributes to increased HUA risk.

Keyphrases

alcohol consumption
gene expression
single cell
uric acid
dna methylation
copy number