Added value of antiphosphatidylserine/prothrombin antibodies in the workup of thrombotic antiphospholipid syndrome: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies.

Arne Vandevelde Walid Chayoua Bas de Laat Gary W Moore Jacek Musial Stéphane Zuily Denis Wahl Katrien M J Devreese

Published in: Journal of thrombosis and haemostasis : JTH (2022)

aPS/PT positivity, especially with high antibody titer, is associated with TAPS diagnosis. Analysis on top of current laboratory criteria is not essential in TAPS diagnosis, but aPS/PT could be useful in patients with thrombosis and a double positive aPL profile (aCL+/aβ2GPI+).

Keyphrases

systemic lupus erythematosus
pulmonary embolism
atrial fibrillation
venous thromboembolism