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Whorling Sclerosing Ependymoma of the Cervical Spinal Cord Presenting Tanycytic Histopathologic Features: A Rare Case Report.

Cumhur Kaan YaltirikEmin Oğuzcan YamanerÖznur SuakarSezin GürkanAydın SavUğur Türe
Published in: International journal of surgical pathology (2022)
Tanycytic ependymoma is a neuroectodermal tumor that arises from ependymoglial cells or tanycytes. It is highly uncommon. We reported a 34-year-old man who was diagnosed with intradural-intramedullary tanycytic ependymoma, located at the level of C4-5 who had a 9-months history of neck pain and left arm pain, and numbness on fingers. One month prior to presentation, his left arm numbness and paresthesia deteriorated. The lesion was removed totally by C4, C5 hemilaminoplasty. The histologic pattern of this lesion was consisted of fascicles forming nebula-like whorling structures. Because of these structures, tanycytic ependymoma should be taken into consideration in the differential diagnosis of a whorling-sclerosing variant of meningiomas.
Keyphrases
  • case report
  • spinal cord
  • induced apoptosis
  • neuropathic pain
  • high resolution
  • chronic pain
  • spinal cord injury
  • cell cycle arrest
  • pain management
  • signaling pathway
  • cell proliferation