Linked-read sequencing identifies abundant microinversions and introgression in the arboviral vector Aedes aegypti.
Seth N RedmondAtashi SharmaIgor SharakhovZhijian TuMaria SharakhovaDaniel E NeafseyPublished in: BMC biology (2020)
Our study shows that inversions are abundant and widely shared among subspecies of Aedes aegypti and that introgression has occurred in regions of secondary contact. This library of 32 novel chromosomal inversions demonstrates the capacity for linked-read sequencing to identify previously intractable genomic rearrangements and provides a foundation for future population genetics studies in this species.