A novel, label-free liquid crystal biosensor for Parkinson's disease related alpha-synuclein.

Xiuxiu YangHaiyu LiXiaofang ZhaoWei LiaoClaire Xi Zhang Zhongqiang Yang

Published in: Chemical communications (Cambridge, England) (2020)

A liquid crystal biosensor based on DNA aptamer for sensitive detection of Parkinson's Disease (PD) related alpha-synuclein was developed. This LC biosensor is constructed using a simple and label free method, and it not only enables early PD diagnosis, but also provides a general platform for detection based on DNA aptamer.

Keyphrases

label free
sensitive detection
circulating tumor
single molecule
quantum dots
cell free
loop mediated isothermal amplification
mass spectrometry
high throughput
wastewater treatment
gold nanoparticles
simultaneous determination
drug induced