Animal studies on postoperative NSAID use after knee surgery suggest that administration of selective and nonselective COX-2 inhibitors may impair healing of soft tissue, bone and tendon-to-bone; however, further clinical studies are needed to better characterize dose and duration dependent risks of NSAIDs.
Keyphrases
- soft tissue
- total knee arthroplasty
- bone mineral density
- anterior cruciate ligament reconstruction
- anti inflammatory
- minimally invasive
- knee osteoarthritis
- patients undergoing
- bone loss
- bone regeneration
- coronary artery bypass
- postmenopausal women
- acute coronary syndrome
- anterior cruciate ligament
- atrial fibrillation
- surgical site infection