Human induced pluripotent stem cells are resistant to human cytomegalovirus infection primarily at the attachment level due to the reduced expression of cell-surface heparan sulfate.
Hideya KawasakiTakahiko HariyamaIsao KosugiShiori MeguroFutoshi IwataKosuke ShimizuYasuhiro MagataToshihide IwashitaPublished in: Journal of virology (2024)
. In the future, drugs targeting HS may become crucial for the treatment of congenital CMV infections. Thus, further research in this area is warranted.