Small extrachromosomal circular DNAs as biomarkers for multi-cancer diagnosis and monitoring.

Xuanmei LuoLili ZhangJian CuiQi AnHexin LiZaifeng ZhangGaoyuan SunWei HuangYifei LiChang LiWenzhuo JiaLihui ZouGang ZhaoFei Xiao

Published in: Clinical and translational medicine (2023)

As independent and stable circular DNA molecules, small eccDNAs in both tissues and plasma can be used as ideal biomarkers for cost-effective multi-cancer diagnosis and monitoring.

Keyphrases

papillary thyroid
squamous cell
gene expression
lymph node metastasis
childhood cancer
cell free
single molecule
young adults