Flexible array coil for cervical and extraspinal (FACE) MRI at 3.0 Tesla.
Frederik AbelEk Tsoon TanMartijn LunenburgCarel van LeeuwenThijs van HoorenMark van UdenCatalina ArteagaJana VincentFraser RobbDarryl SneagPublished in: Physics in medicine and biology (2023)
Objective
High-resolution MRI of the cervical spine (c-spine) and extraspinal neck region requires close-fitting receiver coils to maximize the signal-to-noise ratio (SNR). Conventional, rigid C-spine receiver coils do not adequately contour to the neck to accommodate varying body shapes, resulting in suboptimal SNR. Recent innovations in flexible surface coil array designs may provide three-dimensional (3D) bendability and conformability to optimize SNR, while improving capabilities for higher acceleration factors. 

Approach
This work describes the design, implementation, and preliminary in vivo testing of a novel, conformal 23-channel receive-only flexible array for cervical and extraspinal (FACE) MRI at 3-Tesla (T), with use of high-impedance elements to enhance the coil's flexibility. Coil performance was tested by assessing SNR and geometry factors (g-factors) in a phantom compared to a conventional 21-channel head-neck-unit (HNU). In vivo imaging was performed in healthy human volunteers and patients using high-resolution c-spine and neck MRI protocols at 3T, including MR neurography (MRN). 

Main results
Mean SNR with the FACE was 141-161% higher at left, right, and posterior off-isocenter positions and 4% higher at the isocenter of the phantom compared to the HNU. Parallel imaging performance was comparable for an acceleration factor (R)=2x2 between the two coils, but improved for R=3x3 with mean g-factors ranging from 1.46-2.15 with the FACE compared to 2.36-3.62 obtained with the HNU. Preliminary human volunteer and patient testing confirmed that equivalent or superior image quality could be obtained for evaluation of osseous and soft tissue structures of the cervical region with the FACE.

Significance
A conformal and highly flexible cervical array with high-impedance coil elements can potentially enable higher-resolution imaging for cervical imaging. 
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Keyphrases
- high resolution
- contrast enhanced
- image quality
- magnetic resonance imaging
- mass spectrometry
- endothelial cells
- magnetic resonance
- computed tomography
- diffusion weighted imaging
- high throughput
- healthcare
- end stage renal disease
- air pollution
- tandem mass spectrometry
- single molecule
- quality improvement
- solid state
- peritoneal dialysis
- optical coherence tomography