Resolvin E1, resolvin D1 and resolvin D2 inhibit constriction of rat thoracic aorta and human pulmonary artery induced by the thromboxane mimetic U46619.

Melanie JannawayChristopher TorrensJane A WarnerAnthony P Sampson

Published in: British journal of pharmacology (2018)

These data suggest that resolvins or their mimetics may prove useful novel therapeutics in diseases such as pulmonary arterial hypertension, which are characterized by increased thromboxane contractile activity.

Keyphrases

pulmonary artery
pulmonary arterial hypertension
pulmonary hypertension
coronary artery
endothelial cells
neuropathic pain
spinal cord
skeletal muscle
electronic health record
induced pluripotent stem cells
small molecule
oxidative stress
big data
smooth muscle
spinal cord injury
aortic valve
data analysis