SARS-CoV-2-The Role of Natural Immunity: A Narrative Review.
Sara DianiErika LeonardiAttilio CavezziSimona FerrariOriana IaconoAlice LimoliZoe BouslenkoDaniele NataliniStefania ContiMauro MantovaniSilvano TramonteAlberto DonzelliEugenio SerravallePublished in: Journal of clinical medicine (2022)
this extensive narrative review regarding a vast number of articles highlighted the valuable protection induced by the natural immunity after COVID-19, which seems comparable or superior to the one induced by anti-SARS-CoV-2 vaccination. Consequently, vaccination of the unvaccinated COVID-19-recovered subjects may not be indicated. Further research is needed in order to: (a) measure the durability of immunity over time; (b) evaluate both the impacts of Omicron BA.5 on vaccinated and healed subjects and the role of hybrid immunity.