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Ethnicity-Stratified Analysis of the Association between TNF-α Genetic Polymorphisms and Acute Kidney Injury: A Systematic Review and Meta-Analysis.

Guanzhong ChenBowen LiuHuanqiang LiZiling MaiLiyao ZhangMin LiLiwei LiuShiqun ChenJi-Yan ChenYong Liu
Published in: BioMed research international (2020)
The TNF rs1800629 polymorphism exhibited a trend toward AKI susceptibility with ethnic differences. The relationship was found to be significant among the Asian population, but not among those of Caucasian origin. Additionally, the TNF-α rs1799964 polymorphism was also related to a significantly increased risk of AKI in Asians.
Keyphrases
  • acute kidney injury
  • rheumatoid arthritis
  • cardiac surgery