Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses.

Line EngelbrechtsenYuvaraj MahendranAnna JonssonAnette Prior GjesingPeter E WeekeMarit E JørgensenKristine FærchDaniel R WitteJens J HolstTorben JørgensenNiels GrarupOluf PedersenHenrik VestergaardSigne TorekovJørgen K KantersTorben Hansen

Published in: BMC genetics (2018)

ClinicalTrials.gov ( NCT00289237 ). Trial retrospectively registered at February 9, 2006. Studies were approved by the Ethical Committee of the Central Denmark Region (journal no. 20080229) and by the Copenhagen County Ethical Committee (KA 98155).

Keyphrases

blood glucose
decision making
study protocol
phase iii
copy number
clinical trial
phase ii
insulin resistance
type diabetes
metabolic syndrome
dna methylation
open label
genome wide