Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications.
Burcin IzbudakBerivan CecenIngrid AnayaAmir K MiriAyça Bal-ÖztürkErdal KaraozPublished in: RSC advances (2021)
Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success.
Keyphrases
- tissue engineering
- reduced graphene oxide
- drug delivery
- ionic liquid
- quantum dots
- oxidative stress
- genome wide
- gold nanoparticles
- aqueous solution
- copy number
- highly efficient
- solid phase extraction
- gene expression
- cancer therapy
- mass spectrometry
- risk assessment
- visible light
- human health
- dna methylation
- case control
- climate change
- genome wide identification