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Plug-and-play protein biosensors using aptamer-regulated in vitro transcription.

Heonjoon LeeTian XieXinjie YuSamuel W SchaffterRebecca Schulman
Published in: bioRxiv : the preprint server for biology (2023)
We develop a modular platform for biosensing across a wide dynamic range using aptamer-regulated transcription to detect different proteins and molecular circuits to process the RNA transcript outputs.
Keyphrases
  • transcription factor
  • label free
  • gold nanoparticles
  • sensitive detection
  • magnetic nanoparticles
  • rna seq
  • protein protein
  • amino acid