Plug-and-play protein biosensors using aptamer-regulated in vitro transcription.
Heonjoon LeeTian XieXinjie YuSamuel W SchaffterRebecca SchulmanPublished in: bioRxiv : the preprint server for biology (2023)
We develop a modular platform for biosensing across a wide dynamic range using aptamer-regulated transcription to detect different proteins and molecular circuits to process the RNA transcript outputs.