Plug-and-play protein biosensors using aptamer-regulated in vitro transcription.

Heonjoon Lee Tian Xie Xinjie Yu Samuel W Schaffter Rebecca Schulman

Published in: bioRxiv : the preprint server for biology (2023)

We develop a modular platform for biosensing across a wide dynamic range using aptamer-regulated transcription to detect different proteins and molecular circuits to process the RNA transcript outputs.

Keyphrases

transcription factor
label free
gold nanoparticles
sensitive detection
magnetic nanoparticles
rna seq
protein protein
amino acid