Serial Circulating Tumor DNA in Predicting and Monitoring the Effect of Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer: A Prospective Multicenter Study.
Jiaolin ZhouChangxi WangGuole LinYi XiaoWenzhuo JiaQian LiuBin WuAiwen WuHuizhong QiuFuquan ZhangKe HuHuadan XueZhanlong ShenJiagang HanBeizhan NiuYaping XuZicheng YuLing YangPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
We show that ctDNA is a real-time monitoring indicator that can accurately reflect the tumor burden. The median VAF of baseline ctDNA is a strong independent predictor of MFS.