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The Updated Review on Plant Peptides and Their Applications in Human Health.

Saiprahalad ManiSmruti B BhattVinduja VasudevanDhamodharan PrabhuSundararaj RajamanikandanPalaniyandi VelusamyPalaniappan RamasamyPachaiappan Raman
Published in: International journal of peptide research and therapeutics (2022)
Biologically active plant peptides, consisting of secondary metabolites, are compounds (amino acids) utilized by plants in their defense arsenal. Enzymatic processes and metabolic pathways secrete these plant peptides. They are also known for their medicinal value and have been incorporated in therapeutics of major human diseases. Nevertheless, its limitations (low bioavailability, high cytotoxicity, poor absorption, low abundance, improper metabolism, etc.) have demanded a need to explore further and discover other new plant compounds that overcome these limitations. Keeping this in mind, therapeutic plant proteins can be excellent remedial substitutes for bodily affliction. A multitude of these peptides demonstrates anti-carcinogenic, anti-microbial, anti-HIV, and neuro-regulating properties. This article's main aim is to list out and report the status of various therapeutic plant peptides and their prospective status as peptide-based drugs for multiple diseases (infectious and non-infectious). The feasibility of these compounds in the imminent future has also been discussed.
Keyphrases
  • amino acid
  • human health
  • risk assessment
  • cell wall
  • endothelial cells
  • hepatitis c virus
  • hiv infected
  • human immunodeficiency virus
  • small molecule
  • current status
  • drug induced
  • induced pluripotent stem cells