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Diketopiperazine Gels: New Horizons from the Self-Assembly of Cyclic Dipeptides.

Marco ScarelSilvia Marchesan
Published in: Molecules (Basel, Switzerland) (2021)
Cyclodipeptides (CDPs) or 2,5-diketopiperazines (DKPs) can exert a variety of biological activities and display pronounced resistance against enzymatic hydrolysis as well as a propensity towards self-assembly into gels, relative to the linear-dipeptide counterparts. They have attracted great interest in a variety of fields spanning from functional materials to drug discovery. This concise review will analyze the latest advancements in their synthesis, self-assembly into gels, and their more innovative applications.
Keyphrases
  • drug discovery
  • hydrogen peroxide
  • neural network