Investigation of the role of von Willebrand factor in shear-induced platelet activation and functional alteration under high non-physiological shear stress.
Dong HanWenji SunKiersten P ClarkBartley P GriffithZhongjun Jon WuPublished in: Artificial organs (2023)
High NPSS activates platelets mainly by enhancing the vWF-GPIbα interaction. Platelet activation and receptor shedding induced by high NPSS likely occur through different pathways.
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